Calcavecchia knocked a 6-iron to 6 feet to setup up birdie on No. 11, his second. He made it two straight as his 20-foot birdie try at the next found the bottom of the cup.
The 45-year-old ran home a 40-foot birdie putt at 16 to get to 3 under. Calcavecchia parred four straight around the turn before sinking a 12-foot birdie attempt on the third at Shaughnessy Golf & Country Club.
Calcavecchia stuck a pitching wedge within 5 feet for birdie at four. He dropped a shot at the next as his tee ball came to rest under the lip of a fairway bunker.
The 11-time winner on the PGA Tour got that stroke back at the ninth when he dropped a pitching wedge within 3 feet to set up his final birdie.
'I drove it phenomenal in the Pro-Am Wednesday. That gave me the enthusiasm coming into today's round because if you don't drive it well here, you're cooked,' Calcavecchia said. 'I think I hit 10 fairways today, but still drove it pretty good.'
Glover sank a 7-foot birdie putt on the third to get his round going. On the sixth, the 25-year-old dropped his second shot at the par-4 sixth within 3 feet and kicked that in for birdie.
The South Carolina native drained a 35-foot birdie putt on seven to make it two straight. Glover came right back to sink a 4-footer for birdie at eight. His tee shot at the ninth came to rest under the lip of a bunker.
Glover's second flew into the grand-stands. After a free drop, his third flew the green. He pitched on and two-putted for double bogey to slip back to minus-2.
The two-time All-American at Clemson University started another birdie run at 11. He holed out from a greenside bunker for birdie there, then converted a 15-foot birdie try at the 12th.
Glover dropped a wedge 6 feet from the cup at 13 and sank that effort. He got up and down for birdie from over the green at the short par-4 14th to move to minus-6. However, Glover tripped to a bogey at 15 before parring his final three holes.
'It was feast or famine,' said Glover, who won on the Nationwide Tour in 2003. 'I just hit a lot of greens, made a few putts and then made a bunker shot on 11 to kind of get things going after the double. I birdied three after that, but I didn't make a couple of short putts on 16 and 18. However, you can't be disappointed with 65 around here.'
Jonathan Byrd and Carlos Franco each posted round of 2-under-par 68. They share eighth place with Brent Geiberger, Mathias Gronberg, Michael Allen, J.P. Hayes, Bob Heintz, Scott McCarron, Tom Pernice, Jr. and John Rollins.
Defending champion Vijay Singh opened with a 3-over-par 73. He is well off the pace in a tie for 71st. Ian Leggatt is currently the low Canadian at even-par 70 in a tie for 24th.
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