Boo Weekley fired a 6-under 66 to take second place at 7-under-par 137. Esteban Toledo, Scott Weatherly, Jamie Broce and Tom Johnson were one shot further back at 6-under-par 138.
Dickerson began his second round on the back nine of the Upper Course at Peek 'n Peak Resort and picked up a quick birdie at the par-3 10th. He struggled to a bogey at the par-4 11th, but got that shot back with a birdie at the par-4 15th.
The 24-year-old added a birdie at the par-5 17th to make the turn at 7-under. Dickerson kept on cruising on the front half with a birdie at the par- five second and closed with a birdie at the par-5 ninth to take a two-shot lead into the weekend.
'I tried to play to the middle of the green and give myself putts and not put so much pressure on my putter, always trying to save par after missing a tight pin to the short side,' said Dickerson, whose best finish this year is a tie for 16th at the BellSouth Panama Championship. 'Now, unless I feel really good about hitting it in there, I'll aim left or right of the pin, take my 20- footer and go on.'
Weekley birdied the par-five second and added birdies at the fifth and the eighth to go out in 33. He continued his strong play on the inward nine with a birdie at the par-5 14th.
Weekley then birdied each of his last two holes to finish within striking distance of Dickerson.
'I've been struggling on the weekends for some reason,' said Weekley. 'When the weekend comes along, it's 'we've made it this far now let's just coast through Saturday and Sunday.' Maybe I can change that this week.'
Steve Pate, David Branshaw and Rick Fehr tied for seventh place at 5-under-par 139. Jeff Gove, Deane Pappas, Jimmy Green, Jerry Smith, David McKenzie, Richard S. Johnson and Ryan Hietala shared 10th place at 4-under-par 140.
The 36-hole cut fell at 1-under-par 143 with 69 players qualifying for the weekend. Troy Matteson, who is second on the 2005 Nationwide Tour money list, made the cut on the number after a round of 70.