Zach Johnson matched Boros' 67 to finish as the runner-up for the second straight week on the Nationwide Tour at 20-under-par 268. Ryan Palmer was to shots further back at 18-under-par 270.
After starting the tournament with back-to-back rounds of 64 at Yankee Trace, Boros found himself one shot behind Joe Ogilvie after a third-round 70. However, it didn't take long for Boros to reassume to top spot.
Boros rocketed out of the gate with an eagle at the par-5 first and added four birdies on the outward nine to make the turn at 24-under.
'I didn't see a leaderboard but I kind of figured I was leading at that point,' said Boros. 'I just didn't know by how much.'
The 38-year-old kept plugging along on the back side with back-to-back birdies from the 11th to move to 26-under and open an insurmountable lead.
Boros even bogeyed three straight holes starting at the par-4 15th but his lead was never in doubt. He picked up a par at the closing hole to secure his second title of the season.
'For 14 holes I played as well as I could,' said Boros, who earned $81,000 for the win. 'I leaked a little oil coming in but I had enough of a buffer that I could afford to.'
Boros, who captured the Lake Erie Charity Classic in June, joins Ogilvie as the second multiple winner on the Nationwide Tour. Both players need only one more win to advance to the PGA Tour through the 'battlefield promotion,' which grants an exemption to a player who wins three times in a single season on the Nationwide Tour.
'I hadn't thought about that until a few minutes ago,' said Boros. 'We're going to Chattanooga this week and we'll see what happens.'
Daniel Chopra fired a 9-under 63 to finish seven shots off the lead at 16-under-par 272 alongside Andrew Morse.
Kevin Pendley, Andrew McLardy, Bobby Gage, Bart Bryant and Rich Price were one shot further back at 15-under-par 273.
Ogilvie, who was seeking a battlefield promotion on Sunday, struggled with a final-round 77 to tie for 11th with Craig Bowden and Greg Boyette at 14-under- par 274.
'It was a tough day. Guy made everything and I didn't make much,' said Ogilvie. 'Even if I had played well I would have had a tough time beating him today. You've got to be happy with the way he played. When he's on, he's on and he's tough to beat.'