Tiger Woods, who has never won at this event, Annika Sorenstam, the top player on the LPGA Tour, and defending champion and all-time money and skins leader Fred Couples were shut out on Saturday.
Scott won two skins and $50,000 for the fewest skins on the first day in tournament history, except for 2001. That year, the rules stated that if a player won a skin, they had to validate it on the next hole.
On Sunday, the 10th hole will be worth eight skins and $300,000.
No skins were won on the first hole, but all four players had looks at birdies on the par-4 second. Sorenstam was first to go, but her putt never touched the hole. Scott sank his, then had to watch as the former Masters champions tried to match him and carry the skin to No. 3.
Couples was first and missed his try. Woods' putt from 20 feet hit the left side of the hole, but bounced out and gave Scott his first skins.
'Seeing as how I am the rookie and these guys all have at least a couple of skins, so I've got my name on the board now,' said Scott, a three-time winner on the PGA Tour and reigning Players Champion.
Scott had a chance to sweep all nine skins on Saturday, but Sorenstam stopped him. Scott birdied the par-5 ninth, and Couples was in with par. Woods missed a 6-footer for birdie, but Sorenstam cashed in on a 4-footer to make the 10th hole very valuable.
Both Couples and Woods had chances to win skins, but failed to collect. Woods had 12 feet for birdie to win the fourth, but his putt hit the right edge. Couples failed to convert on an 8-foot birdie try at five, then Scott missed as well to make six worth four skins.
At the par-3 sixth, Woods and Couples hit their tee shots to 4 feet. Woods drained his, then Couples followed making No. 7 worth $150,000.
Woods hit a wedge to 6 feet at the seventh and ran home the birdie putt. Scott answered with a shorter putt to halve the hole and move to the par-3 eighth.
Couples hit a 3-iron into the green and his ball rolled 20 feet from the flag. Woods hit a 4-iron at the 234-yard hole and his shot stopped 24 feet from the stick. Woods badly missed his birdie putt, but Couples had a good look at the putt and the $200,000. Couples' putt came up just short, pushing the ninth to $250,000.
'It's unbelievable,' said Woods. 'That's the way it goes. It's all about timing. Luckily I've been able to make putts that keep it rolling. We all still have a chance.'
The 10th hole will be worth huge money, while holes 11 and 12 will be worth $50,000 each. Holes 13-17 will be worth $70,000 and the closing hole will pay $200,000.