The top-ranked Swede, who led the entire tournament, had four birdies in the final round to finish at 18-under 270 on the Emirates Golf Club's Majlis Course. Helen Alfredsson (67) was second at 276, followed by Karrie Webb (70) at 278.
Sorenstam entered the final round of the European Ladies Tour's season-ending event with a seven-stroke lead.
'I was quite comfortable out there today,' Sorenstam said. 'With a seven-shot lead, I knew all I had to do was not post a big number on any hole. But I was solid and hit a lot of greens, which made it easier.'
Alfredsson, the captain of the 2007 European Solheim Cup team, birdied the first two holes but dropped shots on the next two. She later added five birdies to overtake Webb.
'It was a great way to finish the season,' Alfredsson said. 'I am very happy with the way I played all week, but I had a couple of double bogeys on the first two days.'
Amy Yang (69) finished with back-to-back birdies to tie for fourth place with Veronica Zorzi (70) at 280.
Laura Davies won the Ladies European Tour Order of Merit after Gwladys Nocera failed to win Sunday, and Nikki Garrett of Australia won the rookie of the year award.
'I am proud to have become the rookie of the year and have my name up against such players like Annika Sorenstam, Karrie Webb and Laura Davies,' Garrett said. 'But it was even more fantastic that I could finish the year the way I did.'
Garrett shot a 6-under 66 in the final round to finish at 284.
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