The American started his round on the 10th hole with two straight birdies before losing a stroke on the 12th. He went on to card seven more birdies at the Black Mountain Golf Course.
''Hit some good wedges, some good iron shots. It was good,'' Uihlein said. ''I birdied the first two holes and then duck-hooked into the water on the next.''
Uihlein is a combined 21 under par in the first round of this last three tournaments.
Edberg also had nine birdies, but a pair of bogeys left the Swede a stroke behind.
Scott Jamieson and Javi Colomo (66) share third place.