Pilkadaris breezed past overnight leader Eiji Mizoguchi of Japan, who carded a 4-over par 76 to slump to third place.
Australia's Marcus Both finished the round in second place after shooting a 69.
'The wind was switching around today and was completely different to what we had earlier in the week,' said Pilkadaris, who is chasing his first victory on the Asian Tour.
Early leader Somkiat Srisanga of Thailand, who set a new course record on Thursday with a round of 64, complained of back pain and carded a 75 to fall to fourth, joining Gary Rusnak of the United States, Taiwan's Want Ter-chang, Boonchu Ruangkit of Thailand, David Kang of South Korea and Australian Anthony Summers.
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