Recari, the 25-year-old Spaniard who won her lone LPGA title in 2010, had an 11-under 205 total at Aviara Golf Club.
Hall of Famer Karrie Webb was second after a 70. Winless since the 2011 Founders Cup in Phoenix, Webb dropped strokes with bogeys on Nos. 13 and 17.
Stacy Lewis, playing her first event since taking the No. 1 spot in the world from Yani Tseng with a victory last week in Phoenix, was four strokes back after a 69. Trying to win her third straight tournament, Lewis had an eagle on the par-5 eighth.