Piller, the 23-year-old former Texas A&M player in his first season on the Nationwide Tour, had a 12-under 204 total on The Hills course.
Piller birdied Nos. 14, 15 and 17, but missed a makable birdie putt on 18.
Overall its been a great day and I cant be complaining about that, Piller said.
He enjoyed his late tee time.
Whenever Im playing early I get nervous that I am going to sleep through my alarm, Piller said.
New Zealands Grant Waite (66) and Josh Geary (68) were a stroke back along with American Alex Prugh (69), Australias Jason Norris (71) and Norways Henrik Bjornstad (68) in the event sanctioned by the Australasian and Nationwide tours.
Americans Jim Herman (65), Drew Laning (69) and Jeff Gove (72) were 10 under along with Swedens Jonas Blixt (67). Gove and Norris shared the second-round lead.