Mitchell, from Bloomington, Ill., routed Chris Lange of Bryn Mawr, Penn., 9 and 7 in the morning quarterfinals, and beat Sean Knapp of Oakmont, Penn., 4 and 3 in the afternoon semifinals at Milwaukee Country Club.
Wilson, from St. Martin, Miss., edged Michael Stamberger of Plainfield, N.J., 2-up in the quarterfinals, and Michael McCoy of West Des Moines, Iowa, 3 and 1 in the semifinals.
The champion will receive a spot in the Masters.
The 38-year-old Wilson has checked out of his hotel each day.
We havent stayed in the same hotel twice. We pack up each day because you never know when youre going to go, Wilson said. Just go find an opening. One more night.
Mitchells quarterfinal victory was the second largest in Mid-Amateur history.
Im just out here playing. I wake up every morning and I get to come here and its an absolute treat, said the 30-year-old Mitchell, a former Yankees draft choice as an infielder. I cant really ask for anything more than whats happened so far.