Muirfield last hosted the Open in 2002, when Ernie Els won in a four-man playoff and where Tiger Woods shot 81 in the third round, his highest score as professional, to end his bid for a calendar Grand Slam.
It will be the 16th time the British Open is played at Muirfield, although the 11-year gap is the longest since it went without an Open between 1948 and 1959. Muirfield first hosted the Open in 1892.
Jack Nicklaus won his first claret jug at Muirfield in 1966. Other champions at Muirfield include Nick Faldo (twice), Tom Watson, Lee Trevino, Gary Player, Walter Hagen and Harry Vardon.