Stanford took the lead early with five birdies in a row on the front nine and finished the day with eight birdies. The best round of the tournament so far left the five-time LPGA winner at 8-under 136.
Stanford said she was just trying to make it through the day.
''Finally, I got comfortable on these greens and it felt great. I mean, to see the ball go in that much is a lot of fun,'' the 36-year-old said. ''It was nice to see. I needed a round like that.''
Just like the first round, the contenders played Day 2 at Ko Olina Golf Club with gusty winds - up to 18 mph, according to the National Weather Service.
''I think it's more about putting. I hate to admit this, but I don't always control my trajectory on purpose. It just kind of happens,'' Stanford said. ''When I get into the wind, and I've talked about this with my instructor, for some reason my body just starts moving into the ball more and I tend to keep it lower.''
Hawaii favorite Michelle Wie was one stroke back after a 67 that included five birdies.
Wie made a birdie on the par-5 13th hole that helped her maintain momentum.
''That putt was really, really, really fast. It was downwind, downgrain, downhill and I just barely touched it and I think the crowd rolled that one in for sure,'' Wie said. ''I thought it lipped out for sure, and it just kind of went around then, and so it was awesome.''