Be sure to join the all-new Golf Channel Fantasy Challenge to compete for prizes and form your own leagues, and log on to www.playfantasygolf.com to submit your picks for this week's event.
Danny Lee won this event in a four-man playoff when it was last held in 2015. Here are 10 names to watch in West Virginia:
1. Patrick Reed: Don't look now, but Captain America is on a bit of a tear. Reed has finished T-17 or better each of the last three weeks, highlighted by a T-5 showing at the Travelers Championship, and he cracked the top 30 at Greenbrier in 2014 and 2015.
2. Kevin Kisner: Kisner was among the four-man playoff at Greenbrier the last time the tournament was played, eliminated on the first extra hole. He returns in the midst of a strong season that already includes a win at Colonial and a T-6 finish at the Memorial, plus two other runner-up finishes earlier this year.
3. David Lingmerth: The Swede may have faded over the weekend, but don't be surprised if his name once again drifts toward the top of the leaderboard. Lingmerth has finished T-26 or better in five straight starts and six of his last seven, and his Greenbrier record includes three trips that all resulted in top-20 finishes, including two top-10s.
4. Bill Haas: Haas has been his normal reliable self of late, with four straight top-25 finishes dating back to the Dean & DeLuca Invitational. He missed the cut at Greenbrier in 2015, but he lost in a playoff back in 2011 and was also T-9 in 2013.
5. Phil Mickelson: Mickelson will be making his much-anticipated first start with a new caddie on the bag, and he'll do so against a relatively weak field this week and off a run that includes three straight top-30 finishes. Mickelson should be well-rested after skipping the U.S. Open and will look to buck a trend of three straight missed cuts here from 2011-13.
6. Tony Finau: The long-hitter has displayed an ability to thrive on some tighter tracks, notably his success this year at Innisbrook and his T-13 showing at Greenbrier last year. Finau has finished T-29 or better in four of his last five starts overall and appears on the cusp of a second PGA Tour win.
7. Danny Lee: Lee finally gets a chance to defend his title, two years after he notched his first win on Tour. He returns to West Virginia on a bit of a hot streak, with three finishes of T-6 or better over his last six starts. That includes a T-3 finish at TPC River Highlands two weeks ago, and Lee also tied for 16th at Greenbrier in 2014.
8. Keegan Bradley: The former PGA champ has started to turn things around this year, including top-10 finishes each of the last two weeks. Bradley tied for fourth at Greenbrier in 2014 and has never missed a cut here in four prior appearances, lending credence to the notion that he might contend this week for what would be his first win since 2012.
9. Webb Simpson: Simpson has won just once since his surprise U.S. Open title five years ago, but he has a history of success amid the West Virginia mountains. Simpson finished third in 2014 and also cracked the top 10 in both 2011 (T-9) and 2012 (T-7), and he tied for eighth in Connecticut two weeks ago in his most recent start.
10. J.B. Holmes: Holmes is another player who frequently makes the trip to Greenbrier, with five made cuts in six prior appearances. Each of those made cuts has led to a finish of T-27 or better, including a T-22 finish two years ago, and Holmes has made three straight cuts including a 12th-place showing at Erin Hills.