Cabrera salvaged a par at the last, while his fellow competitors sunk, one-by-one, to give the 32-year-old Argentine the title at the Benson & Hedges International in Sutton Coldfield, England.
To win a big tournament such as this is great, really great, and I hope this can be the start of a really good season for me, said Cabrera, who moved to sixth on the Volvo Order of Merit (money list).
Cabrera talks about his win
Cabrera shot 3-under 69 to finish the event at 10-under-par 278, one shot clear of overnight leader Barry Lane. Lane, who was seeking his first tour victory in eight years, shot 1-over 73 Sunday. Colin Montgomerie (69), Padraig Harrington (69) and Michael Campbell (70) tied for third place at 8-under.
Cabrera started the final round three back of Lane, and managed to wrest away the lead with a birdie at the drivable par-4 10th. A bogey, however, at the 11th dropped him into a six-way tie for the top spot.
What ensued was an abundance of birdies and bogeys from all those challenging for the title.
Cabrera hit the green in two on the par-5 17th, and two-putted for birdie. He then caught a break at the 473-yard finishing hole, as his 2-iron approach shot flirted with the water, but came to rest in a spectators bag.
He was awarded a free drop and pitched wonderfully to two feet, from where he tapped in to finish at minus 10.
Lane blew his chance for victory by three-putting the 16th for bogey, and failing to make birdie on the 17th.
Montgomerie had to be the most dejected, though, as he dropped three shots on the 10th and 18th holes. The 38-year-old Scot hit his tee shot over the green at No. 10, and then pitched his second shot into the water fronting the putting surface. He recorded a double bogey, but recovered with birdies on 11, 14, 15 and 17.
Needing a birdie at the last, Montgomerie hit a wayward drive, which forced him to lay up short of the water-guarded green. He eventually made bogey to finish two back.
Likewise, Harrington and Campbell also bogeyed the 18th when needing birdie.
John Daly shot 2-under 70 to finish at 5-under-par, tied for ninth place.
Full-field scores from the Benson & Hedges International