'I'm extremely disappointed to miss the British Open for the second consecutive year,' Norman said in a statement. 'But I've always maintained there's nothing more important than family and friends.'
The 46-year-old Australian missed last year's Open Championship because of hip surgery.
Norman, who won this event in 1986 and 1993, was at Royal Lytham early Wednesday and was to play a practice round with New Zealand's Michael Campbell before withdrawing.
Japanese player Toshimitsu Izawa also pulled out on Wendesday because of illness.
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