At 13-under 131, the 30-year-old Swede suddenly finds herself three shots better than Emilee Klein (66) and Kate Golden (65), while overnight co-leader Tina Fischer shot a second-round 70 to end in solo fourth at 9-under.
When Sorenstam is on, the game appears anything but difficult.
The six-time winner for 2001 took to the Rail Course seemingly without a care in the world, and after a string of stock pars up front, struck first with a birdie at the par-5 5th, and then quickly added another at the 6th.
One more red number at No. 8, and Sorenstam was out in a fine 33.
Three more birdies against not a single bogey over the last nine holes, and she was in with a perfectly-crafted 66.
Sorenstam hit 17 greens in regulation and was her usual self from the tee ' down the middle nearly ever time. As a result, her 36-hole score matched the tournament record, set originally by Laura Davies in 1994.
The real strength of my game is in my irons, she let on following the round. Thats how Ive been scoring as well as I have in the last few weeks.
More like the last few months.
For the year, Sorenstam has racked up not just six wins ' including a major at the Nabisco Championship ' but also four additional seconds and a third. Earlier in the season, she became the first-ever woman to shoot a 59 in competition.
Said Klein: Shes the best player in the world right now. She has no weaknesses in her game. Shes a great, great player.
So great that Sorenstam is on the verge of running away with an event she hasnt played since 94. She finished in 28th on that occasion.
After taking last week off, Sorenstam is also gunning for two wins in as many starts ' she won earlier in the month at the Canadian Women's Open.
In addition to the first-place prize this week of $150,000 is an additional $100,000 that will be awarded to the champion of the State Farm LPGA Series race.
You guessed it. Sorenstam will probably win that one too. Shes got a 100-point lead on everyone else.
Click Here for for Full-Field Scores from the State Farm Rail Classic.