Botes posted a 5-under-par 67 for a total four-day score of 14-under 274. He leads by three strokes over third round leader, 18-year-old Belgian, Nicolas Colsaerts.
The big news following this fourth of six total qualifying rounds was the cut that was established for the top-75 players and ties. That mark fell at 4-over-par 292, and included 80 players.
Unfortunately, for 86 other hopefuls, there will be no more play this week. And there will be no European Tour on their plates for the next golfing season.
However, for the 26-year-old Botes, he likes his chances for this week's conclusion, not to mention next year's prospects.
'I think the European Tour is a good place to gain experience, and I want to win here and get the No. 1 card,' he said following his round of 67.
Other notable players who will continue their journey this week are Justin Rose, Graeme Storm, Iain Pyman, Philip Walton and Simon Dyson.
Dyson's story Monday was particularly interesting, as his fourth round score of 65 has not been bettered by any of the other participants this week.
And, as it is, he survives into Tuesday by just one shot at 3-over 291. Had the Englishman shot a 67, which is a mighty fine score in it's own, he would have been going home.
'That is definitely one of the best rounds I've shot under pressure, although strangely enough I didn't feel it.'
Many are feeling it right about now, albeit in a much different context; former European Tour winners Peter Fowler, Peter Hedblom and Ove Sellberg did not make the cut.
The top-35 players following Tuesday's and Wednesday's final rounds will qualify for playing privileges for next year's tour.