Moore claimed the top spot at 3-over-par 145.
'The morning rounds are easier to score because the wind is down,' said Moore. 'I'll take it. I'd have taken another solid round like I had (Saturday), but it got a little better than that.'
Toni Wiesner was one stroke further back at 4-over-par 146 after firing a 69 on Sunday. Carolyn Creekmore and Cecilia Mourge D'Algue shared third place at plus-five.
Four-time champion Carol Semple Thompson shared ninth at plus-9.
Beatriz Arenas, who led after the opening round of stroke play, struggled to an 11-over 82. That dropped her into a tie for 11th at 10-over-par 152.
Two-time defending champion Diane Lang ended in 14th after the stroke-play portion at 11-over-par 153.
Patricia French notched the seventh known hole in one in championship history on the par-3 16th. She carded a 78 and shared 27th to advance to match play.
Kate Johnson, Kim Cure, Lindsay Wortham, Lisa Stanley, Martha Lang, Nancy Fitzgerald, Patricia Robinson and Frances Gacos claimed the final eight spots in the match play portion of the championship via a playoff.
The first round of match play will take place Monday, with two rounds on Tuesday and Wednesday. The 18-hole final will take place on Thursday.