Woods was one of several players this week battling the flu. That ailment got the best of him, as the world's No. 1 player bogeyed his final two holes Friday to make the cut on the number of 1-over-par 143.
The Nissan Open has long been a nemesis for Woods, who has never won this tournament. He played this event twice as an amateur and this was his ninth start at Riviera as a professional. This marks the most starts at any PGA Tour event without a win for Woods.
Woods was looking to win his third straight start of 2006. He was triumphant in his start of the season three weeks ago at the Buick Invitational, defeating Nathan Green and Jose Maria Olazabal in a playoff.
The 30-year-old also won in his only European Tour start of the year two weeks ago at the Dubai Desert Classic, where he bettered then World No. 5 Ernie Els in a playoff.
Prior to this week, Woods had withdrawn twice in his career. The first time was at the 1995 U.S. Open as an amateur, when he injured his wrist in a shot from thick rough.
The other time was in 1998 at the AT&T Pebble Beach National Pro-Am. That withdrawal came when the tournament's finish was delayed six months due to bad weather and Woods chose not to return and complete the event.