Sorenstam's 1-up win in 21 holes gets her a third-round match with Rachel Hetherington, who is ranked 48th in this event. Hetherington advanced thanks to a 5 and 4 drubbing of Mi Hyun Kim.
Karrie Webb, the former No. 1 who is seeded 29th this week, knocked out No. 4 Paula Creamer, 2 and 1. Webb will take on Jeong Jang, the 13th-ranked player in the field. Jang moved on with a 1-up victory over amateur Shinobu Moromizato.
Christina Kim, No. 30, matched the largest rout on Friday as she dispatched Laurie Rinker, 5 and 3. Kim will face 14th-ranked Wendy Ward on Saturday after Ward outlasted Silvia Cavalleri, 2 and 1.
Jennifer Rosales also posted a 5 and 3 win on Friday against Hall of Famer Beth Daniel. Rosales, the 21st seed, is set to take on No. 60, Marisa Baena in the third round. Baena needed one extra hole to defeat Grace Park.
Ai Miyazato, who gained entry into the field because she is the Japanese LPGA Tour's leading money winner, squeaked out a 1-up win over Juli Inkster. Miyazato, the 43rd seed, will battle Sophie Gustafson, No. 59, who bettered Shi Hyun Ahn in 19 holes.
Candie Kung, ranked No. 8, also needed one playoff hole to beat Leta Lindley. That gets her a match Saturday morning with 56th-seeded A.J. Eathorne, who edged Dorothy Delasin, 1-up.
Nicole Perrot, who held the second-round lead last week at the U.S. Women's Open, continued her fine play as she trounced 10th seed, Gloria Park, 4 and 3. Perrot, ranked 42nd, will meet Pat Hurst, the 39th seed, on Saturday after Hurst birdied the 18th for a 1-up win over Wendy Doolan.