Weekley claimed his first PGA TOUR victory at 14-under 270, winning by just one shot over Ernie Els, who missed a hole-out eagle by only a foot at the last hole.
World No. 3 Els is the highest-ranked player in this year's field. Stewart Cink, Brandt Snedeker and Steve Flesch, who all finished inside the top five at the Masters on Sunday, are also set to play.
The GOLF CHANNEL will have three hours of coverage on the first two days.
Next week is the Byron Nelson Championship, where last season Scott Verplank claimed his first win in six years.