Enloe defeated Weekley in a playoff on Sunday to win the Pete Dye Classic, benefiting from a four-shot swing over the final three holes and then knocking his playing partner off with a par on the first extra hole to claim his first Nationwide Tour victory.
Trailing Weekley by four shots after both made birdie at 15, Enloe added a birdie at the 16th and closed with another at the 18th to finish off a round of 4-under 68 and force the playoff.
Weekley, who had led following both of the previous two rounds, bogeyed 16 and 18 to close with a 2-under 70.
The players ended at 14-under-par 274, then headed to the 18th again for the playoff.
Enloe and Weekley were just short of the green on their approaches at the playoff hole -- similar to the spot where Weekley made a bogey from in regulation.
Weekley chipped within 12 feet and missed his par putt left. Enloe chipped inside Weekley, then rolled in a 7-footer for the win.
'This feels great,' said Enloe, who hit 13 of 14 fairways Sunday at Pete Dye Golf Club.
The $108,000 check he collected was not enough to get Enloe inside the top 20 on the money list. The top 20 at the end of the season garner full-time membership on the PGA Tour.
'This year has been a struggle,' he admitted. 'I haven't played poorly this year, I just don't have any good finishes to show for it. Hopefully this will lead to big things for me.
The playoff bogey was a disappointing end to an up-and-down round for Weekley, who was also seeking his first Nationwide Tour win and the coveted first-place money that would all but guarantee him a bump to the PGA Tour next season.
After winning $64,800 for second place, Weekley moved to 11th on the money list.
'I'm just aggravated that I didn't give him a fight on the last hole,' he said after the loss.
Weekley lost his lead early after bogeying three straight holes from the fourth, then got it back while he birdied six of the next nine holes. But his near-miss on a long par put at the 16th signaled the beginning of the end.
Next came a missed 7-foot birdie try at the 17th, then a bogey from short of the green at the 18th, where he lipped out a 5-foot par putt.
Meanwhile, Enloe made a 7-foot birdie putt at the 16th to all of a sudden become a threat. At the 18th, with the ball sitting well above his feet, he knocked his approach to within 8 feet to set up another birdie and force the playoff.
Weekley missed his par putt at 18 after Enloe had made his birdie.
'It just wasn't meant to be,' Weekley said. 'But there's so many ways to get in the top 20. We'll continue to play every week, play as hard as we can and see where the dust settles.'
Jason Allred closed with a 2-under 70 to finish alone in third place at 12-under 276. Jim Rutledge, John Mallinger and Jamie Broce tied for fourth place, one stroke further back.