Creamer, Tseng and U.S. Women’s Amateur champion Danielle Kang will play the first two rounds together.
Tseng won the Wegmans LPGA Championship in a 10-shot runaway Sunday. Creamer finished tied for third. It was Tseng's sixth worldwide title this year.
“It’s going to be fun, going against somebody who’s going to be in contention, for sure,” Creamer told GolfChannel.com. “That’s the person you have to beat right now. She’s playing great golf. Who else would you want to be paired with?”
Creamer, 24, heads to the Broadmoor looking to become the first player since Karrie Webb in 2000 and ’01 to win back-to-back U.S. Women’s Opens.
Tseng will be looking to complete the career grand slam at just 22.
“It’s impressive what she’s done,” Creamer said. “You can’t take that away from her. I just have to work harder, and make more putts and make less mistakes. She is raising the bar right now. I can’t let her get too far away.
“Playing the first two days with her will be nice, kind of where you know what the competition’s doing. At the same time, it’s two days of a four-day event.'
Creamer, Tseng and Kang will go off the first tee at 1:36 p.m. Thursday and off the 10th at 8:06 a.m. on Friday.