Hubert Green is alone in third place at 7-under-par 137, followed by Morris Hatalsky, who shot a 2-under 70 to finish two rounds at 6-under-par 138.
This tournament has been hampered by weather problems as Friday's opening round was washed away with very few players making it to the course. Saturday's action was delayed by an hour due to a passing storm. All players completed 36 holes.
Lietzke opened his second round on the back nine at The Westin Savannah Harbor Resort and Spa. He left himself with short birdie putts at his first two holes and converted those chances to break into red figures very quickly.
At the 14th hole, a hole that was playing 324 yards but was shortened to 291 yards for the second round, Lietzke hit his drive pin high but off the green. Lietzke chipped in from 48 feet for eagle as he 4-under through his first five holes.
'I think they shortened it up, hoping we'd all knock it on,' said Lietzke, referring to 14. 'I had a lucky chip-in. It would have gone five or six-feet past and it hit the pin dead on and went in.'
Lietzke kept the strong play going with a 14-footer for birdie at the 15th. He saved a brilliant par at the 17th when he got up and down after an eight-footer.
Lietzke wedged his approach to three feet to set up birdie at No. 1. He parred the next two holes and drained an 18-foot birdie putt at the par-5 fourth. Lietzke parred his final five holes and is in good position for his first title of 2003 and his sixth since joining the Champions Tour in 2001.
'I'm disappointed not to make a few more birdies coming in,' said Lietzke, who won the team portion of this event with Bill Rogers last year. 'I had some makeable putts and didn't make anything. But I didn't struggle too much out there.'
Quigley flew out of the gate in the second round Saturday. He collected three birdies in his first four holes, including two from tap-in range. He sank a 20-footer for birdie at the par-5 15th to polish off a front-nine, 4-under 32.
Quigley knocked an 8-iron to three feet to set up birdie at No. 2 but dropped the only stroke of his round to par when drove near a tree at the fourth. He holed a 12-foot birdie putt at six to complete his round of 5-under 67.
'I'm okay being a shot back,' said Quigley. 'It might make me aggressive tomorrow. With Lietzke up there, I'll have to shoot low to win. He's too good a player.'
Hale Irwin (69), Fuzzy Zoeller (71) and Bob Gilder (69) are tied for fifth place at 5-under-par 139. Vicente Fernandez, the first-round leader, shot a 1-over 73 in the second round and shares eighth with Rodger Davis and David Eger. That trio stands at 4-under-par 140.