Enloe parred the first extra hole for his first win on tour. He was helped by a four-stroke swing in the final three holes.
Weekley led by four after both players birdied No. 15. Enloe went on to birdie 16 and 18, while Weekley bogeyed the same two holes to force the extra session.
This the fourth year of the tournament and it has been contested each year at the Pete Dye Golf Club.
GOLF CHANNEL has two hours of coverage the first two days and three hours of action on Saturday and Sunday.
Next week is the Utah EnergySolutions Championship, where Craig Kanada won last year.